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Generation and Rearrangements of Ylides from Tertiary Amines and α-Diazo Ketones − Very High Catalytic Activity of [RuCl(η5-C5H5)(PPh3)2]

✍ Scribed by Alessandro Del Zotto; Walter Baratta; Francesca Miani; Giancarlo Verardo; Pierluigi Rigo


Publisher
John Wiley and Sons
Year
2000
Tongue
English
Weight
278 KB
Volume
2000
Category
Article
ISSN
1434-193X

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✦ Synopsis


The reaction of N,N-dimethyl-2-propen-1-amine, N,N-dimethylbenzylamine and N,N-dimethyl-2-propyn-1-amine with the α-diazo ketones N 2 CHCOR [R = Me (2a), Et (2b), nPr (2c), iPr (2d), (CH 2 ) 10 Me (2e), (CH 2 ) 14 Me (2f) or Ph (2g)] in a 1:1 molar ratio, catalysed by the complex [RuCl(η 5 -C 5 H 5 )(PPh 3 ) 2 ] (1) (1% mol), have been investigated. Noticeably, the corresponding α-amino ketones 3a-g, 4a-g and [a