✦ LIBER ✦

Generation and measurement of interleukin-1, interleukin-2, and mitogen levels in small volumes of whole blood

✍ Scribed by Mark Lyte

Book ID: 102311404
Publisher: John Wiley and Sons
Year: 1987
Tongue: English
Weight: 465 KB
Volume: 1
Category: Article
ISSN: 0887-8013
DOI: 10.1002/jcla.1860010114

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✦ Synopsis

Whole blood assays that allow simultaneous performance of IL-1 and IL-2 production as well as lymphocyte mitogen responsiveness are described. The advantages to these techniques are: (1) small volume of sample required (1 mi of whole blood or less), (2) time required to perform the assays (1 0 min), and (3) use of whole blood rather than isolated cells in the evaluation of immune competency which is more reflective of the in vivo condition. The techniques described lend themselves to application in the clinical setting.

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