Generation and intramolecular cyclization of difluoroalkyl radicals via single electron transfer from the benzeneselemolate anion: Synthesis of α,α-difluoro-γ-lactams

✍ Scribed by Kenji Uneyama; Takeo Yanagiguchi; Hideki Asai

• Publisher: Elsevier Science
• Year: 1997
• Tongue: French
• Weight: 150 KB
• Volume: 38
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(97)10073-9

✦ Synopsis

Sewsl a,adiflw1w74scts

(2) were pqxucd by radical cycliion of amides (1) wbicb wscinitiatcd by a single electron transfer (SET) process from the bmzneselmolate anion. De&laurion of these lactams (2)gave the umeq&iq a,adifhmn+xcm&yk lactams I$).