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Generation and immune-characterization of single chain fragment variable (scFv) antibody recognize breast cancer cells line (MCF-7)

โœ Scribed by Mahgoub, Ilham; Bolad, Ahmed K; Mergani, Mohamed


Book ID
121536326
Publisher
Springer (Biomed Central Ltd.)
Year
2014
Tongue
English
Weight
73 KB
Volume
2
Category
Article
ISSN
2051-1426

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## Background The ability of cytosine deaminase (CD) to convert the antifungal agent 5-fluorocytosine (5-FC) into one of the most potent and largely used anticancer compound such as 5-fluorouracil (5-FU) raised considerable interest in this enzyme to model gene or antibody โ€“ directed enzyme-prodrug