𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Generation and function of human regulatory CD8+ T cells induced by a humanized OKT3 monoclonal antibody hOKT3γ1(Ala-Ala)

✍ Scribed by Vitaly Ablamunits; Kevan C. Herold


Book ID
116532137
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
224 KB
Volume
69
Category
Article
ISSN
0198-8859

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


NKG2A is a marker for acquisition of reg
✍ Vitaly Ablamunits; Octavian Henegariu; Paula Preston-Hurlburt; Kevan C. Herold 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 435 KB 👁 1 views

## Abstract Treatment with anti‐CD3 mAb modulates immune responses that cause type 1 diabetes and other diseases. CD8^+^ Tregs can be induced in vitro and in vivo by mAb. However, 1/3 of patients do not respond to drug therapy and in an equal proportion, anti‐CD3 mAb does not induce Tregs in vitro.