The metabolism of tertiary amines is mediated primarily by cytochrome P-450 and MFAO, leading to alpha-C oxidation and N-oxidation, respectively. We have discussed how lipophilicity, basicity, steric hindrance, and stereochemistry can effect the outcome of metabolism as well as species, sex, and age
β¦ LIBER β¦
Generation and fate of enamines in the microsomal metabolism of cyclic tertiary amines
β Scribed by L.M. Sayre; D.A. Engelhart; B. Venkataraman; M.K.M. Babu; G.D. McCoy
- Book ID
- 115764513
- Publisher
- Elsevier Science
- Year
- 1991
- Tongue
- English
- Weight
- 590 KB
- Volume
- 179
- Category
- Article
- ISSN
- 0006-291X
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