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Generation and Diels-Alder reactions of t-butyl 2H-azirine-3-carboxylate

✍ Scribed by Maria José Alves; Thomas L Gilchrist


Book ID
108387041
Publisher
Elsevier Science
Year
1998
Tongue
French
Weight
187 KB
Volume
39
Category
Article
ISSN
0040-4039

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Lewis acid-catalyzed hetero Diels–Alder
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Activation by Lewis acids of 3-alkyl and 3-phenyl 2H-azirines promotes their participation in hetero Diels-Alder reactions with a variety of dienes. This methodology circumvents the previous requirement of an electron-withdrawing carboxyl moiety at the 3-position of the 2H-azirine.

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