Generation and characterization of LymphoStat-B, a human monoclonal antibody that antagonizes the bioactivities of B lymphocyte stimulator
β Scribed by Kevin P. Baker; Bryan M. Edwards; Sarah H. Main; Gil H. Choi; Ruth E. Wager; Wendy G. Halpern; Patrick B. Lappin; Todd Riccobene; Donara Abramian; Les Sekut; Bonnie Sturm; Carol Poortman; Ralph R. Minter; Claire L. Dobson; Elizabeth Williams; Sara Carmen; Rodger Smith; Viktor Roschke; David M. Hilbert; Tristan J. Vaughan; Vivian R. Albert
- Publisher
- John Wiley and Sons
- Year
- 2003
- Tongue
- English
- Weight
- 303 KB
- Volume
- 48
- Category
- Article
- ISSN
- 0004-3591
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A human monoclonal antibody type IgG4, designated 1Ff4, was obtained by Epstein Barr virus transformation of peripheral blood lymphocytes from a hepatitis B vaccinee (HB-VAX: plasmaderived vaccine) after one boost of yeast recombinant DNA derived vaccine (Engerix-B). 1Ff4 binds preferentially to HBs