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Generation and characterization of LymphoStat-B, a human monoclonal antibody that antagonizes the bioactivities of B lymphocyte stimulator

✍ Scribed by Kevin P. Baker; Bryan M. Edwards; Sarah H. Main; Gil H. Choi; Ruth E. Wager; Wendy G. Halpern; Patrick B. Lappin; Todd Riccobene; Donara Abramian; Les Sekut; Bonnie Sturm; Carol Poortman; Ralph R. Minter; Claire L. Dobson; Elizabeth Williams; Sara Carmen; Rodger Smith; Viktor Roschke; David M. Hilbert; Tristan J. Vaughan; Vivian R. Albert


Publisher
John Wiley and Sons
Year
2003
Tongue
English
Weight
303 KB
Volume
48
Category
Article
ISSN
0004-3591

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✍ R.A. Heijtink; J. Kruining; P. van Bergen; S. de Rave; J. van Hattum; M. Schutte πŸ“‚ Article πŸ“… 2002 πŸ› John Wiley and Sons 🌐 English βš– 204 KB

A human monoclonal antibody type IgG4, designated 1Ff4, was obtained by Epstein Barr virus transformation of peripheral blood lymphocytes from a hepatitis B vaccinee (HB-VAX: plasmaderived vaccine) after one boost of yeast recombinant DNA derived vaccine (Engerix-B). 1Ff4 binds preferentially to HBs