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Generation and Characterization of High Affinity Humanized Fab Against Hepatitis B Surface Antigen

✍ Scribed by Ashutosh Tiwari; Durgashree Dutta; Navin Khanna; Subrat K. Acharya; Subrata Sinha


Book ID
107581711
Publisher
Humana Press Inc
Year
2009
Tongue
English
Weight
418 KB
Volume
43
Category
Article
ISSN
1073-6085

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The Fab fragment was cloned from the monoclonal cell line TAPC301-CL4, which was produced using the Epstein-Barr virus (EBV) transformation method. This cell line produces a human monoclonal antibody (CL4MAb) against the hepatitis B surface antigen (HBsAg). This MAb was shown to have hepatitis B vir