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Generation and characterization of antigen-specific CD4+, CD8+, and CD4+CD8+ T-cell clones from patients with carbamazepine hypersensitivity

✍ Scribed by Wu, Ying; Farrell, John; Pirmohamed, Munir; Park, B. Kevin; Naisbitt, Dean J.

Book ID
119279026
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
303 KB
Volume
119
Category
Article
ISSN
1097-6825

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## Background: We have previously established tumour t-cell lines, both from the skin and from the blood of patients with a cutaneous t-cell lymphoma (ctcl). in one patient, the tumour cells and the derived cell lines had a cd3+ cd4+ cd8- phenotype and a trisomy of chromosome 7. they expressed thre