Generalized Inferences on the Overall Treatment Effect in Meta-analysis with Normally Distributed Outcomes

✍ Scribed by Lili Tian

• Publisher: John Wiley and Sons
• Year: 2008
• Tongue: English
• Weight: 104 KB
• Volume: 50
• Category: Article
• ISSN: 0323-3847
• DOI: 10.1002/bimj.200710409

✦ Synopsis

Abstract

This paper focuses on inferences about the overall treatment effect in meta‐analysis with normally distributed responses based on the concepts of generalized inference. A refined generalized pivotal quantity based on t distribution is presented and simulation study shows that it can provide confidence intervals with satisfactory coverage probabilities and perform hypothesis testing with satisfactory type‐I error control at very small sample sizes. (© 2008 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)