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Generalised dystonia with an abnormal magnetic resonance imaging signal in the basal ganglia: A case of adult-onset GM1 gangliosidosis

✍ Scribed by Jaume Campdelacreu; Esteban Muñoz; Beatriz Gómez; Teresa Pujol; Amparo Chabás; Eduardo Tolosa


Publisher
John Wiley and Sons
Year
2002
Tongue
English
Weight
394 KB
Volume
17
Category
Article
ISSN
0885-3185

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✦ Synopsis


Abstract

We describe a 46‐year‐old woman with adult‐onset generalised dystonia and a severe speech disorder with an abnormal magnetic resonance imaging signal in the basal ganglia. A storage disease study demonstrated the presence of a GM1 gangliosidosis. This rare condition should be investigated in cases of generalised dystonia, especially in those cases with other features suggesting symptomatic dystonia. © 2002 Movement Disorder Society