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General Synthesis of Highly Functionalized Cyclopentane Segments for the Preparation of Jatrophane Diterpenes †

✍ Scribed by Lentsch, Christoph; Rinner, Uwe


Book ID
118037424
Publisher
American Chemical Society
Year
2009
Tongue
English
Weight
504 KB
Volume
11
Category
Article
ISSN
1523-7060

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Toward a Total Synthesis of Macrocyclic
✍ Johann Mulzer; Gerald Giester; Michael Gilbert 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 German ⚖ 354 KB

## Abstract A total synthesis of the biologically potent jatrophane diterpenes pepluanin A (**1**) and euphosalicin A (**2**) is being aimed at. __En route__ to these targets, a concise synthesis of the nonracemic cyclopentane building block **74** was developed. Key steps were a __Claisen–Eschenmo