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General report on the second international workshop on chromosomes in leukemia

✍ Scribed by J. D. Rowley

Publisher
John Wiley and Sons
Year
1980
Tongue
French
Weight
263 KB
Volume
26
Category
Article
ISSN
0020-7136

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✦ Synopsis

Abstract

The Workshop participants were able to establish that the t(8;21) and t(15;17) are each definitely associated with a particular type of ANLL, namely, AML‐M2 and APL‐M3 and M3 variant, respectively. Both translocations, particularly the t(15;17), have an uneven geographical distribution which cannot presently be explained. The data also show that patients with preleukemia and an abnormal karyotype have a very poor prognosis with a fatal outcome in 60%, compared with only 30% for patients with a normal karyotype.

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