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## Abstract A general multistage (stepwise) procedure is proposed for dealing with arbitrary gatekeeping problems including parallel and serial gatekeeping. The procedure is very simple to implement since it does not require the application of the closed testing principle and the consequent need to
Constitutive relations and numerical integration algorithms for elasto/viscoplastic problems are investigated. A fully implicit integration scheme is adopted and the relevant expression of the consistent tangent operator for yield criteria and ยฏow functions of arbitrary type is derived by suitably g
Advances in genomic and proteomic profiling of disease have transformed the field of molecular diagnostics, thus leading the way for a major revolution in clinical practice. While the range of tests for disease detection and staging is rapidly expanding, many physicians lack the knowledge required t