𝔖 Bobbio Scriptorium
✦   LIBER   ✦

General methods of alkaloid synthesis. XII. The total synthesis of (±)-isoretronecanol and (±)-δ-coniceine

✍ Scribed by Robert V. Stevens; Yuhshi Luh; Jenq-Tsong (Jim) Sheu

Publisher
Elsevier Science
Year
1976
Tongue
French
Weight
178 KB
Volume
17
Category
Article
ISSN
0040-4039

No coin nor oath required. For personal study only.

✦ Synopsis

The pyrrolizidine nucleus (1) is incorporated into a relatively large number of alkaloids,' of which isoretronecanol (Z), trachelanthamidine (3) and platynecine (4) may be regarded as typical. " C&OH 0 ti k

📜 SIMILAR VOLUMES

General methods of alkaloid synthesis. X
General methods of alkaloid synthesis. XIII. the total synthesis of (±)-ipalbidine and (±)-septicine
✍ Robert V. Stevens; Yuhshi Luh 📂 Article 📅 1977 🏛 Elsevier Science 🌐 French ⚖ 178 KB

## Recently, we reported' the total synthesis of (*)-isoretronecanol (1) and (+)-8-coniceine (2). A key step in each of these syntheses utilized the acid-catalyzed rearrangement of a cyclopropylimine to generate the 3-phenylthio-2-pyrroline synthon (2). The latter intermediate serves as a relative