General Method for the Rapid Solid-Phase Synthesis of Large Numbers of Peptides: Specificity of Antigen--Antibody Interaction at the Level of Individual Amino Acids

A rapid method for the preparation of am

A rapid method for the preparation of amino acid resin esters for merrifield solid-phase peptide synthesis

✍ Michael W. Monahan; Chaim Gilon 📂 Article 📅 1973 🏛 Wiley (John Wiley & Sons) 🌐 English ⚖ 389 KB 👁 2 views

## Abstract An improved method for the preparation of Merrifield resin esters is presented. This method is rapid, is free of racemization, and is not complicated by a quaternization side reaction. Chloromethylated resin beads, __t__‐butoxycarbonyl amino acid, and potassium __t__‐butoxide are heated