provides a favorable soil. In the case of breast carcinoma, the final step in bone metastasis (namely bone destruction) is mediated by osteoclasts that are stimulated by local production of the tumor peptide parathyroid hormone-related peptide (PTH-rP), whereas prostate carcinomas stimulate osteobla
General mechanisms of metastasis
โ Scribed by Elisa C. Woodhouse; Rodrigo F. Chuaqui; Lance A. Liotta
- Publisher
- John Wiley and Sons
- Year
- 1997
- Tongue
- English
- Weight
- 133 KB
- Volume
- 80
- Category
- Article
- ISSN
- 0008-543X
No coin nor oath required. For personal study only.
โฆ Synopsis
target cell surface and extracellular proteins that mediate sensing, extracellular matrix degradation, adhesion, and motility (i.e., adhesion Address for reprints: Elisa C. Woodhouse, Laboreceptors, degradative enzymes and their inhibitors, and proliferative/ ratory of Pathology, Division of Clinical Scimotility-stimulating cytokines). ences, National Cancer Institute, National Insti-Bone is the third most common site of metastasis. Certain tututes of Health,
๐ SIMILAR VOLUMES
The molecular changes associated with the transition of melanoma cells from radial growth phase to vertical growth phase (metastatic phenotype) are not very well defined. Expression of the tyrosine-kinase receptor c-KIT progressively decreases during local tumor growth and invasion of human melanoma
Acoustic streaming is a stationary fluid motion induced by intense ultrasound. This paper describes the mechanism of generation of acoustic streaming, theoretically and experimentally. A qualitative explanation in relation to acoustic radiation pressure is followed by a detailed discussion based on
The acquisition by tumor cells of the ability to metastasize is the critical event in the clinical course of most human neoplastic disease. While metastasis plays a pivotal role in the ultimate success or failure of therapy, it is in fact a result of a more insidious malignant process termed tumor p
Version 23037 - 2011-03-04 18:04:04 +0100