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General Mechanism for Chiral Recognition by Native and Modified Cyclodextrins

✍ Scribed by Koji Kano; Ryuhei Nishiyabu

Book ID
110431060
Publisher
Springer Netherlands
Year
2002
Tongue
English
Weight
91 KB
Volume
44
Category
Article
ISSN
0923-0750

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MECHANISMS FOR CHIRAL RECOGNITION BY CYC
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✍ Koji Kano 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 101 KB

The mechanisms for chiral recognition by cyclodextrins (CDxs) are discussed. Examples of host-guest systems where the 'lock-and-key mechanism' and the 'three-point rule' are applicable are cited and discussed. Most results reported so far suggest that the ability of native CDxs and chemically modifi

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✍ Vydyula Pavan Kumar; Perepogu Arun Kumar; Iragavarapu Suryanarayana; Yadavalli V 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 German ⚖ 124 KB

## Abstract The two pyrrolidinylidenesulfamido‐modified __β__‐cyclodextrins (__β__‐CDs) **3** and **4** were prepared and studied for chiral discrimination of the enantiomers (__R__)‐ and (__S__)‐**1** of zolmitriptan. The pyrrolidinylidenesulfamido spacer improved the chiral discrimination and bin