๐”– Bobbio Scriptorium
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General Discussion


Book ID
102310382
Publisher
Wiley (John Wiley & Sons)
Year
1956
Tongue
English
Weight
463 KB
Volume
47
Category
Article
ISSN
0095-9898

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โœฆ Synopsis


Gamma-globulins do not crystallize. This in- dicates that they are heterogeneous, as pointed out by Dr. Putnam.

I agree very much with what Dr. Spiegelman said. When I spoke of heterogeneity by site of formation, I did not want to limit that to different organs. Different subcellular sites may just as well be responsible for the formation of hcterogenous proteins.

I want to bring up another point vcry early in the meeting -one rclated to Dr. Haurowitz' prcscntationand this is the Pauling-Corey helix. Unquestionably, the unstrctched and stretched forms of keratin have, respectively, the a-helix and pleated sheet structures of Pauling and Corey. Collagen, on the other hand, has a structure that has not yct been predicted, but that is probably quite simple. S o doubt it will be necessary to abandon the idea of tlic structural equivalence of the amino acid residues ; there is no compulsion on nature to construct proteins only according to this principle.


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