๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

General approach to prostaglandins via methylenecyclopentanones. Total synthesis of (+-)-prostaglandin F2.alpha.

โœ Scribed by Stork, Gilbert; Isobe, Minoru


Book ID
111693796
Publisher
American Chemical Society
Year
1975
Tongue
English
Weight
216 KB
Volume
97
Category
Article
ISSN
0002-7863

No coin nor oath required. For personal study only.


๐Ÿ“œ SIMILAR VOLUMES


Novel synthesis of prostaglandin F2.alph
โœ Woodward, R. B.; Gosteli, J.; Ernest, I.; Friary, R. J.; Nestler, G.; Raman, H.; ๐Ÿ“‚ Article ๐Ÿ“… 1973 ๐Ÿ› American Chemical Society ๐ŸŒ English โš– 355 KB
Total synthesis of prostaglandins. V. A
โœ J.B. Heather; Rattan Sood; Philip Price; George P. Peruzzotti; Sang.S. Lee; Hsu ๐Ÿ“‚ Article ๐Ÿ“… 1973 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 225 KB

We wish to report the synthesis of prostaglandin E2 (PGE2, &) via conjugate addition of the vinyl cupratez, derived from trans-3(E)-(l-ethoxyethoxy)l-iodo-l-octene (3b), to 2-(6-carbomethoxy-~-2-hexenyl)-4(R)-(2-tetrahydropyranyloxy)-2-cyclopenten-l-one (s). We also describe herein a novel synthesis