General approach for the synthesis of polyquinanes: stereospecific, regiospecific entry into the tetracyclo-[6.6.0.01,5.08,12]tetradecane system

General approach for the synthesis of po

General approach for the synthesis of polyquinenes via the weiss reaction. Preparation of the chiral tetracyclo [6.6.0.01,5.08,12]tetradecane-3,6,10,13,-tetraene

✍ M. Venkatachalam; M. Jawdosiuk; M. Deshpande; J.M. Cook 📂 Article 📅 1985 🏛 Elsevier Science 🌐 French ⚖ 257 KB

The aldol approach to construct the tetracyclic polyquinane skeleton of l2, followed by hydroboration and the HMPA mediated dehydration of four hydroxyl groups has resulted in the facile synthesis of the chiral polyquinene, tetracyclo[6.6.D.01t5.08\*12]telrddocane-3,6,10,13\_tetraene 2. This method