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Gene–environment interactions in human lung cancer

✍ Scribed by Aage Haugen; David Ryberg; Steen Mollerup; Shan Zienolddiny; Vidar Skaug; Debbie H Svendsrud

Book ID
119540951
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
74 KB
Volume
112-113
Category
Article
ISSN
0378-4274

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The p53 tumour suppressor gene is at the crossroads of a network of cellular pathways including cell cycle checkpoints, DNA repair, chromosomal segregation, and apoptosis. These pathways have evolved to maintain the stability of the genome during cellular stress from DNA damage, hypoxia, and activat