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Gene–based sequence–tagged–sites (STSs) as the basis for a human gene map

✍ Scribed by Berry, Rebecca; Stevens, T.J.; Walter, Nicole A.R.; Wilcox, Andrea S.; Rubano, Todd; Hopkins, Janet A.; Weber, James; Goold, Richard; Soares, Marcelo Bento; Sikela, James M.


Book ID
109916696
Publisher
Nature Publishing Group
Year
1995
Tongue
English
Weight
678 KB
Volume
10
Category
Article
ISSN
1061-4036

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A total of 405 unique single base-pair substitutions, located within the ATG translation initiation codons (TICs) of 255 different genes, and reported to cause human genetic disease, were retrieved from the Human Gene Mutation Database (HGMD). Although these lesions comprised only 0.7% of coding seq