Gene transfer to skeletal muscle by site-specific delivery of electroporation and ultrasound
β Scribed by Yuanli Li; Junqing Wang; Andrew Satterle; Qunqiang Wu; Jue Wang; Feng Liu
- Book ID
- 116303655
- Publisher
- Elsevier Science
- Year
- 2012
- Tongue
- English
- Weight
- 429 KB
- Volume
- 424
- Category
- Article
- ISSN
- 0006-291X
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## Abstract We showed that a __LacZ__ expression plasmid (pCAGβlacZ) injection followed by electroporation increased the expression of the __LacZ__ gene in the skeletal muscles of adult __mdx__ mice up to ninefold higher as compared with simple intramuscular DNA injection. When fullβlength mouse dy