## Background: The major advantage in choosing non-viral vectors such as cationic polymers for in vitro and in vivo transfection is their higher biosafety than viral ones. among the cationic polymers, polyethylenimines (peis) are promising molecules for gene delivery to a variety of cells. efficien
โฆ LIBER โฆ
Gene-transfer systems for human endothelial cells
โ Scribed by S.G Martin; J.C Murray
- Book ID
- 114176696
- Publisher
- Elsevier Science
- Year
- 2000
- Tongue
- English
- Weight
- 92 KB
- Volume
- 41
- Category
- Article
- ISSN
- 0169-409X
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Heme oxygenase (HO-1) is a stress protein that has been suggested to participate in defense mechanisms against agents that induce oxidative injury such as hemoglobin/heme, hypoxia-ischemia and cytokines. Overexpression of HO-1 in endothelial cells (EC) might, therefore, protect against oxidative str