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Gene Transfection of Lung Cells in Vitro and in VIVO

โœ Scribed by Hazinski, T A


Book ID
118170127
Publisher
Annual Reviews
Year
1993
Tongue
English
Weight
983 KB
Volume
55
Category
Article
ISSN
0066-4278

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We explored poly(4-vinylimidazole) (P4V) as a nonviral gene carrier. We show that P4V can form DNA condensates of small size (<110 nm) using a dye-exclusion assay with ethidium bromide and dynamic light scattering, and that the complexes form in a pHsensitive manner, due to the amphotericity of the