Gene transcription abnormalities in canine atopic dermatitis and related human eosinophilic allergic diseases

Heterogeneity of CD80 gene transcription

Heterogeneity of CD80 gene transcription by human keratinocytes to allergens and irritants: relevance to allergic contact dermatitis in vivo

✍ Paul Wakem; Francisco Ramirez; David Zlotnick; Anthony A. Gaspari 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 170 KB

## Abstract Using an __in vitro__ assay for CD80 promoter activity, the transcriptional response of primary cultured human keratinocytes from different donors in response to allergens and irritants was studied. The CD80 promoter activity was increased reproducibly after exposure to certain chemical