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Gene therapy with HSV-TK of pancreatic cancer cell lines: Different responses to GCV treatment

โœ Scribed by Greco, Eliana; Fogar, Paola; Basso, Daniela; Parolin, Cristina; Stefani, Annalisa; Pasquali, Claudio; Plebani, Mario; Pedrazzoli, Sergio


Book ID
123603529
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
202 KB
Volume
118
Category
Article
ISSN
0016-5085

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To examine the immunological mechanisms involved in cancer gene therapy using the herpes simplex virus thymidine kinase (HSV-tk) gene and ganciclovir (GCV), murine hepatocellular carcinoma (HCC) cells, BNL1ME A.7R.1, were transduced retrovirally with the HSV-tk gene. HSV-tk-transduced cells exhibite