Cancer gene therapy with HSV-tk/GCV syst
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Shigeki Kuriyama; Masaji Kikukawa; Kazuhiro Masui; Hirotsugu Okuda; Toshiya Naka
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Article
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1999
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John Wiley and Sons
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French
โ 620 KB
To examine the immunological mechanisms involved in cancer gene therapy using the herpes simplex virus thymidine kinase (HSV-tk) gene and ganciclovir (GCV), murine hepatocellular carcinoma (HCC) cells, BNL1ME A.7R.1, were transduced retrovirally with the HSV-tk gene. HSV-tk-transduced cells exhibite