## Abstract We present a tumor gene therapy approach based on the use of regulatory sequences of the H19 gene that are differentially expressed between normal and cancer cells. We constructed expression vectors carrying the gene for the A fragment of diphtheria toxin (DTβA) or herpes simplex virus
Gene therapy vectors harboring AFP regulatory sequences
β Scribed by Shuichi Kaneko; Taiki Tamaoki
- Book ID
- 111640227
- Publisher
- Humana Press Inc
- Year
- 2001
- Tongue
- English
- Weight
- 137 KB
- Volume
- 19
- Category
- Article
- ISSN
- 1073-6085
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## Abstract ## Background Malignant tumors of the liver are among the most common causes of cancerβrelated death throughout the world. Current therapeutic approaches fail to control the disease in most cases. This study seeks to explore the potential utility of transcriptional regulatory sequences