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Gene Therapy of Cancer || Gene-Directed Enzyme Prodrug Cancer Therapy

✍ Scribed by Karjoo, Zahra

Book ID
126859314
Publisher
Elsevier
Year
2014
Weight
555 KB
Category
Article
ISBN
0123942950

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## Abstract ## Background Gene‐directed enzyme prodrug therapy (GDEPT) based on the __E. coli__ enzyme purine nucleoside phosphorylase (PNP) represents a new approach for treating slow growing tumours like prostate cancer (PCa). Expressed enzyme converts a systemically administered prodrug, fludar