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Gene therapy grows bone in mice and rats

✍ Scribed by Nathan Seppa

Book ID
115061115
Publisher
Society for Science & the Public
Year
2000
Tongue
English
Weight
525 KB
Volume
157
Category
Article
ISSN
0036-8423

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## Abstract Hypothalamic leptin gene therapy normalizes the mosaic skeletal phenotype of leptin‐deficient __ob/ob__ mice. However, it is not clear whether increased hypothalamic leptin alters bone metabolism in animals already producing the hormone. The objective of this study was to evaluate the l