𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Gene Targeting in ES Cells

✍ Scribed by Soriano, Philippe

Book ID
118240484
Publisher
Annual Reviews
Year
1995
Tongue
English
Weight
505 KB
Volume
18
Category
Article
ISSN
0147-006X

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The ability to contribute to the germ line is the most important experimental feature of embryonic stem (ES) cells. Using ES cells, it is possible to introduce targeted mutations into any gene and to derive the corresponding mutant mice. A common problem with this technology is that the ES cells oft