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Gene-specific requirement of RNA polymerase II CTD phosphorylation

✍ Scribed by Julie Drogat; Damien Hermand


Book ID
115082075
Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
392 KB
Volume
84
Category
Article
ISSN
0950-382X

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Regulation of RNA polymerase II activity
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## Abstract The carboxyl‐terminal domain (CTD) of the largest subunit of mammalian RNA polymerase II (RNAP II) consists of 52 repeats of a consensus heptapeptide and is subject to phosphorylation and dephosphorylation events during each round of transcription. RNAP II activity is regulated during t