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Gene set-based module discovery in the breast cancer transcriptome

✍ Scribed by Atsushi Niida; Andrew D Smith; Seiya Imoto; Hiroyuki Aburatani; Michael Q Zhang; Tetsu Akiyama

Book ID
114998889
Publisher
BioMed Central
Year
2009
Tongue
English
Weight
818 KB
Volume
10
Category
Article
ISSN
1471-2105

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## Abstract The antineoplastic agent doxorubicin inhibits cell growth through mechanisms that include an interaction with iron, resulting in the generation of cytotoxic reactive oxygen species (ROS). Prior studies have shown that the wild‐type hemochromatosis gene (wt HFE) may downregulate iron upt