Signal transduction in the aging immune
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Amir A Sadighi Akha; Richard A Miller
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Article
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2005
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Elsevier Science
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English
β 142 KB
T cells from aged mice show defects in the early stages of the activation process, including alterations in cytoskeletal reorganization that precede discrimination, by the T cell receptor, of agonist from antagonist peptides. Aging also modifies the pattern of glycosylation of T cell surface macromo