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Gene profiling of Chikungunya virus arthritis in a mouse model reveals significant overlap with rheumatoid arthritis

✍ Scribed by Nakaya, Helder I.; Gardner, Joy; Poo, Yee-Suan; Major, Lee; Pulendran, Bali; Suhrbier, Andreas

Book ID: 118752652
Publisher: John Wiley and Sons
Year: 2012
Tongue: English
Weight: 650 KB
Volume: 64
Category: Article
ISSN: 0004-3591
DOI: 10.1002/art.34631

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## Abstract ## Objective Cytotoxic T lymphocyte–associated antigen 4 (CTLA‐4) is a negative regulator of T cells and is, therefore, a strong candidate susceptibility gene for T cell–mediated autoimmune diseases. The association of CTLA‐4 single‐nucleotide polymorphisms (SNPs) with rheumatoid arthr