Gene mutations causing autosomal dominant cerebellar ataxia in Japan
β Scribed by Ishikawa, Kinya; Mizusawa, Hidehiro
- Book ID
- 122017429
- Publisher
- Elsevier Science
- Year
- 2010
- Tongue
- English
- Weight
- 69 KB
- Volume
- 68
- Category
- Article
- ISSN
- 0168-0102
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## Abstract ## Background: Sporadicβonset ataxia is common in a tertiary care setting but a significant percentage remains unidentified despite extensive evaluation. Rare genetic ataxias, reported only in specific populations or families, may contribute to a percentage of sporadic ataxia. ## Meth
Autosomal dominant cerebellar ataxias (ADCAs) are clinically and genetically heterogeneous neurodegenerative disorders. The aim of this study was to evaluate electrophysiologically peripheral nervous system involvement in each of the groups studied and its correlation with the number of CAG repeats.