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Gene linkage analysis in the mouse by somatic cell hybridization: Assignment of adenine phosphoribosyltransferase to chromosome 8 and α-galactosidase to the X chromosome

✍ Scribed by Christine Kozak; Elizabeth Nichols; Frank H. Ruddle


Book ID
112558735
Publisher
Springer
Year
1975
Tongue
English
Weight
1003 KB
Volume
1
Category
Article
ISSN
1572-9931

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A specific enzyme immunoassay of uroporphyrinogen decarboxylase was developed and applied to the detection of the human enzyme in man-rodent somatic cell hybrids. This method allowed to assign the gene for uroporphyrinogen decarboxylase to human chromosome 1.