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Gene-gene interaction between interleukin-6 and α2-macroglobulin influences the risk for Alzheimer's disease

✍ Scribed by Metin Bagli; Andreas Papassotiropoulos; Frank Jessen; Marie Luise Rao; Wolfgang Maier; Reinhard Heun


Publisher
John Wiley and Sons
Year
2000
Tongue
English
Weight
117 KB
Volume
47
Category
Article
ISSN
0364-5134

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It is now known that possession of one of the three common forms of the apolipoprotein E gene (allele 4) confers an increased risk for Alzheimer's disease (AD), both familial and sporadic, and that this risk is dose-dependent. Other genes that may play a role in AD, either through independent associ