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Gene-gene Interaction among Candidate Gene Polymorphisms is Associated with Total IgE Levels in Children with Asthma

✍ Scribed by Seo, J.; Choi, W.; Kang, M.; Kim, B.; Kwon, J.; Kim, J.; Kim, B.; Yu, J.; Hong, S.


Book ID
119283571
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
49 KB
Volume
125
Category
Article
ISSN
1097-6825

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IL10 is an anti-inflammatory cytokine that has been found to have lower production in macrophages and mononuclear cells from asthmatics. Since reduced IL10 levels may influence the severity of asthma phenotypes, we examined IL10 singlenucleotide polymorphisms (SNPs) for association with asthma sever