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Gene flaw found in induced stem cells

✍ Scribed by Dolgin, Elie


Book ID
109824181
Publisher
Nature Publishing Group
Year
2010
Tongue
English
Weight
317 KB
Volume
464
Category
Article
ISSN
0028-0836

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In an attempt to study the regulatory properties of cells required for gene amplification, the capacity for amplification of the dehydrofolate reductase gene (dhfr) was determined in F9 teratocarcinoma stem cells during differentiation. By stepwise selection of surviving cells exposed to progressive