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Gene expression via direct injection of plasmid vector into the thymus

✍ Scribed by H. Li; R.J. Bartlett; R. Pastori; N.S. Kenyon; C. Ricordi; R. Alejandro


Book ID
117234907
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
117 KB
Volume
29
Category
Article
ISSN
0041-1345

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## Abstract ## Background Although nuclear transport of therapeutic genes is an essential requirement of human gene therapy, factors required for nuclear entry of DNA remain to be elucidated. Non‐viral vector systems have led to numerous improvements in the efficiency of delivery of exogenous DNA