Molecular mechanism of suppression of MD
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Tran Thi Hien; Hyung Gyun Kim; Eun Hee Han; Keon Wook Kang; Hye Gwang Jeong
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Article
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2010
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John Wiley and Sons
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English
⚖ 375 KB
Multidrug resistance (MDR) is a major obstacle in cancer chemotherapy and its inhibition is an effective way to reverse cancer drug resistance. In the present study, we investigated that puerarin, a natural isoflavonoid from Pueraria lobata, down-regulated MDR1 expression in MCF-7/adriamycin (MCF-7/