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Gene expression profiling in polycythaemia vera: overexpression of transcription factor NF-E2

✍ Scribed by Philipp S. Goerttler; Clemens Kreutz; Johannes Donauer; Daniel Faller; Thomas Maiwald; Edith März; Brigitta Rumberger; Titus Sparna; Annette Schmitt-Gräff; Jochen Wilpert; Jens Timmer; Gerd Walz; Heike L. Pahl

Book ID
108673106
Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
736 KB
Volume
129
Category
Article
ISSN
0007-1048

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✍ Atsuko Sakurai; Michie Nishimoto; Seiichiro Himeno; Nobumasa Imura; Masafumi Tsu 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 358 KB

## Abstract Thioredoxin reductase (TrxR) is a selenoprotein that catalyzes the reduction of the active site disulfide of thioredoxin (Trx), which regulates the redox status of the cells. In the present study, we found that TrxR1, one of the three TrxR isozymes, was induced by cadmium as well as tum