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Gene expression profiling elucidates a specific role for RARγ in the retinoic acid-induced differentiation of F9 teratocarcinoma stem cells

✍ Scribed by Dan Su; Lorraine J. Gudas


Book ID
113488441
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
775 KB
Volume
75
Category
Article
ISSN
0006-2952

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Mouse F9 embryonic teratocarcinoma stem cells can be induced to differentiate into visceral endoderm. Following retinoic acid (RA) treatment, alpha-fetoprotein (AFP), a differentiation marker, is expressed and secreted. The mechanism by which RA regulates AFP expression during differentiation is not