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Gene expression profiling distinguishes JAK2V617F-negative from JAK2V617F-positive patients in essential thrombocythemia

✍ Scribed by Puigdecanet, E; Espinet, B; Lozano, J J; Sumoy, L; Bellosillo, B; Arenillas, L; Álvarez-Larrán, A; Solé, F; Serrano, S; Besses, C

Book ID
109886464
Publisher
Nature Publishing Group
Year
2008
Tongue
English
Weight
331 KB
Volume
22
Category
Article
ISSN
0887-6924

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Clinical correlates of JAK2V617F allele
Clinical correlates of JAK2V617F allele burden in essential thrombocythemia
✍ Jaya Kittur; Ryan A. Knudson; Terra L. Lasho; Christy M. Finke; Naseema Gangat; 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 198 KB

## Abstract ## BACKGROUND. __JAK2__V617F occurs in approximately 50% of patients with essential thrombocythemia (ET). Qualitative studies of mutation analysis have previously reported an association between __JAK2__V617F and advanced age, higher hemoglobin level, higher leukocyte count, and lower