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Gene expression profiling defines the role of ATP-exposed keratinocytes in skin inflammation

✍ Scribed by Ohara, Hiroshi; Saito, Rumiko; Hirakawa, Satoshi; Shimada, Miki; Mano, Nariyasu; Okuyama, Ryuhei; Aiba, Setsuya


Book ID
119293580
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
402 KB
Volume
58
Category
Article
ISSN
0923-1811

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## Abstract Epidermal keratinocytes respond to extracellular influences by activating cytoplasmic signal transduction pathways that change gene expression. Using pathway‐specific transcriptional profiling, we identified the genes regulated by two such pathways, p38 and ERK. These pathways are at th