Gene expression profiling changes induced by a novel Gemini Vitamin D derivative during the progression of breast cancer

Osteopontin induces multiple changes in

Osteopontin induces multiple changes in gene expression that reflect the six “hallmarks of cancer” in a model of breast cancer progression

✍ Amy C. Cook; Alan B. Tuck; Susan McCarthy; Joel G. Turner; Rosalyn B. Irby; Greg 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 101 KB

## Abstract Tumor progression is a multistep process, which enables cells to evolve from benign to malignant tumors. This progression has been suggested to depend on six essential characteristics identified as the “hallmarks of cancer,” which include: self‐sufficiency in growth signals, insensitivi