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Gene expression profiling and functional analysis of angiogenic markers in murine collagen-induced arthritis

✍ Scribed by Yvonne Raatz, Saleh Ibrahim, Marc Feldmann, Ewa M Paleolog

Book ID: 120705130
Publisher: BioMed Central
Year: 2012
Tongue: English
Weight: 723 KB
Volume: 14
Category: Article
ISSN: 1478-6354
DOI: 10.1186/ar3922

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## Abstract ## Objective There is evidence that interleukin‐4 (IL‐4) plays a major role in the induction of extracellular matrix protein synthesis in fibrotic disease. We therefore examined the effect of IL‐4 on collagen synthesis in primary fibroblasts isolated from normal and TSK/+ mice, which s